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CVE-2026-17583: The affected Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files

30
Routine
HIGH 8.4UPGRADEUPGRADEUPGRADE

CVE-2026-17583 is a high-severity flaw (CVSS 8.4) affecting abi prism 310 data collection software, abi prism 3100\/3100-avant data collection software, applied biosystems 3130 series data collection software. Below: why it ranks where it does, which versions are affected, what to do, and the exact commands.

The affected Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

Why this priority

  • High severity

A fixed release or distro patch exists.

Risk facts

CVSS score8.4 (High)
Attack vectorLocal
Attack complexityLow
Privileges neededNone
User interactionNone
EPSS exploit chance0.1% (top 97%)
CISA exploited listNo
WeaknessCWE-353
Published2026-08-05
Last modified2026-08-26
Publisher (CNA): ICS-CERT · Vendor: thermofisher

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Last updated 2026-08-26 · Sources: CVE Program, NVD, CISA KEV, EPSS and vendor advisories · How we score

Am I affected?

Timeline

thermofisher abi prism 310 data collection software UPGRADE
Affected: <= 3.1
Fixed in: newer than 3.1
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy abi-prism-310-data-collection-software || rpm -q abi-prism-310-data-collection-software || abi-prism-310-data-collection-software --version
2. UPGRADE to newer than 3.1 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade abi-prism-310-data-collection-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade abi-prism-310-data-collection-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
thermofisher abi prism 3100\/3100-avant data collection software UPGRADE
Affected: <= 2.0
Fixed in: newer than 2.0
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy abi-prism-31003100-avant-data-collection-software || rpm -q abi-prism-31003100-avant-data-collection-software || abi-prism-31003100-avant-data-collection-software --version
2. UPGRADE to newer than 2.0 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade abi-prism-31003100-avant-data-collection-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade abi-prism-31003100-avant-data-collection-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
thermofisher applied biosystems 3130 series data collection software UPGRADE
Affected: <= 4.1
Fixed in: newer than 4.1
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy applied-biosystems-3130-series-data-collection-software || rpm -q applied-biosystems-3130-series-data-collection-software || applied-biosystems-3130-series-data-collection-software --version
2. UPGRADE to newer than 4.1 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade applied-biosystems-3130-series-data-collection-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade applied-biosystems-3130-series-data-collection-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
thermofisher applied biosystems 3500\/3500xl series data collection software UPGRADE
Affected: < 4.0.3
Fixed in: 4.0.3
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy applied-biosystems-35003500xl-series-data-collection-software || rpm -q applied-biosystems-35003500xl-series-data-collection-software || applied-biosystems-35003500xl-series-data-collection-software --version
2. UPGRADE to 4.0.3 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade applied-biosystems-35003500xl-series-data-collection-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade applied-biosystems-35003500xl-series-data-collection-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
thermofisher applied biosystems 3730\/3730xl series data collection software UPGRADE
Affected: < 5.0.3
Fixed in: 5.0.3
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy applied-biosystems-37303730xl-series-data-collection-software || rpm -q applied-biosystems-37303730xl-series-data-collection-software || applied-biosystems-37303730xl-series-data-collection-software --version
2. UPGRADE to 5.0.3 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade applied-biosystems-37303730xl-series-data-collection-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade applied-biosystems-37303730xl-series-data-collection-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
thermofisher applied biosystems seqstudio flex series instrument software UPGRADE
Affected: < 1.2.1
Fixed in: 1.2.1
Safe to downgrade to: no unaffected older release
1. Check installed version
apt-cache policy applied-biosystems-seqstudio-flex-series-instrument-software || rpm -q applied-biosystems-seqstudio-flex-series-instrument-software || applied-biosystems-seqstudio-flex-series-instrument-software --version
2. UPGRADE to 1.2.1 (Debian / Ubuntu)
sudo apt update && sudo apt install --only-upgrade applied-biosystems-seqstudio-flex-series-instrument-software
2. UPGRADE (RHEL / Amazon Linux / Fedora)
sudo dnf upgrade applied-biosystems-seqstudio-flex-series-instrument-software
Note
Distros often backport fixes without changing the version number. Confirm with the distro advisory or changelog.
Verify at the official source NVD · CVE Program · Report a problem with this page
Scores and fixes here are computed automatically from those and other public sources. Confirm with the vendor advisory before changing production systems.

Quick answers

How do I fix CVE-2026-17583?

abi prism 310 data collection software: upgrade to newer than 3.1; abi prism 3100\/3100-avant data collection software: upgrade to newer than 2.0; applied biosystems 3130 series data collection software: upgrade to newer than 4.1. Exact commands for each OS are on this page.

Is CVE-2026-17583 being exploited?

CVE-2026-17583 is not on the CISA Known Exploited Vulnerabilities list at the time of the last update. Check again, as this can change.

What does CVE-2026-17583 affect?

CVE-2026-17583 affects abi prism 310 data collection software, abi prism 3100\/3100-avant data collection software, applied biosystems 3130 series data collection software. Severity is high (CVSS 8.4). The affected Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

How urgent is CVE-2026-17583?

Priority 30/100. High severity

References

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